Saturday, December 28, 2013

Odor in the City

Brief review of this week's strange odors:

Dallas, Texas — A mysterious odorwas reported this Saturday, December 27th by hundreds of locals.
At about 11:40 a.m., the first call of a "strange chemical odor" came from the Mid State United Recycling facility. It was found that the odor was a result of a byproduct created during the recycling of motor oil.
"Whatever piece of equipment they use for this process heated up to the point that it started venting out of the facility," Evans said.
Evans said HazMat reported the byproduct is not hazardous.
"And it may take some time for the smell to dissipate," he said.
Andy Rodriguez, a resident in the area, said the smell spurred concern.
"I don't know if I should go home or not because I'm not sure if it's gas, or just a smell like gas," she said.
Authorities are still investigating the incident to confirm whether the smell is indeed the result of the motor oil recycling process.

La Jolla, California: A non-profit organization is taking legal action over the noxious odor at La Jolla Cove.
“Citizens for Odor Nuisance Abatement” is suing the city of San Diego, Interim Mayor Todd Gloria and the state of California.
According to the Complaint, the plaintiffs claim it’s the city’s responsibility to keep the public area free of the offensive smell, which it has failed to do.

What to Do About Smelly La Jolla Cove
The group says the city is to blame because of a fence erected along the sidewalk that spans the cove. Because people don’t have access to the rocks anymore, birds and sea lions can climb higher up the bluffs to defecate, they claim.
The complaint alleges that people have become sick and nearby businesses have lost revenue because of the odor. According to the lawsuit, boxer Floyd Mayweather booked two villas and six rooms at the La Valencia hotel, only to leave 15 minutes later because of the smell, costing the hotel more than $5,000 in one day.
Owners of the La Valencia Hotel and George’s By the Cove – two prominent La Jolla businesses – say the city is dragging its feet to fix the smell problem, which many believe is a growing issue.
Some locals that spoke with NBC 7 Friday, December 27, 2013 said the fences designed to keep people off the bluffs are making the sea lions feel more at home in La Jolla, adding to the waste problem.
Mother and son Nancy and Michael Garcia visited La Jolla Cove Friday and said the stench was unbearable

Plainview, New York. The Nassau County Fire Marshal’s Hazardous Materials Division was called to a Plainview neighborhood Wednesday after reports of a noxious odor near the Old Bethpage Village restoration. The division was tasked with determining the source and cause of the smell, which residents described as a mix between rotten eggs, sewage and gas, 1010 WINS’ Gary Baumgarten reported Thursday, December 26, 2013.

New Castle, UK  An investigation is under way after a fire on board a ferry in the North Sea forced it to return to Newcastle.
RAF helicopters winched two passengers and four crew off the MS King Seaways, which was sailing to Amsterdam, when it was 30 miles off Flamborough Head.Passenger Jamie Petterson said that people were "generally very calm and in reasonable spirits" when the initial fire alarm sounded, but that he later encountered "a strong smell of smoke".

Saturday, December 14, 2013

You are unique. And so is your sense of smell.

The 400 genes responsible for our olfaction noses can vary greatly  - with more  than 900,000 variations of those genes. And even if your genomes are similar, the receptors can be about 30 percent different.

It's very commonif one person likes a certain smell and the other person doesn't. But a surprise finding by Duke researchers shows that no two people smell things the same way. They are very different at the receptor levels 

Genes code odor receptors, but how are these receptors activated? Researchers from Duke, Rockefeller University, University of Pennsyklvania and Monnell
identified 27 receptors that had a significant response to at least one odorant they used in the study thus doubling the number of known odorant-activated receptors (now 40).

So we are now one little step closer to understanding the consequences of these receptor activation and understanding the sense of smell. 


The missense of smell: functional variability in the human odorant receptor repertoire, Joel D Mainland, Andreas Keller, et al. Nature Neuroscience, Early online Dec. 8, 2013. DOI: 10.1038/nn.3598

Monday, December 2, 2013

Learning to become afraid and passing it to children

Animals can pass on information about a traumatic experience to their offsprings. Researchers at Yerkes National Primate Research Center, Emory University have found that when a mouse learns to become afraid of a certain odor, his or her pups will be more sensitive to that odor, even though the pups have never encountered it. This is an example of an "epigenetic" alteration: transmitted not in the letter-by-letter sequence of the DNA, but in its packaging or chemical modifications.

In mice taught to fear cherry-blossom-smelling chemical
acetophenone, the odorant receptor gene that responds to this compound has a changed pattern of methylation while 
the sequence of the gene encoding the receptor that responds to the odor remained unchanged. And it's all because DNA from the sperm of smell-sensitized mice is altered. As senior author of the study Kerry Ressler says. "There is some evidence that some of the generalized effects of diet and hormone changes, as well as trauma, can be transmitted epigenetically."